Tag: genetic mutations
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Predicting Hepatocellular Carcinoma Outcomes Using a Novel Model Based on Anoxia Resistance and the Effect of the ERBB Pathway
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Hepatocellular carcinoma (HCC) is considered one of the most prevalent types of cancer, topping the list of diseases that pose a significant global health challenge due to its high mortality rate and low long-term survival rates. Despite remarkable advances in targeted therapy and immunotherapy, there remains an urgent need to…
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Comprehensive Genetic Testing Program for Breast Cancer Detection at the Hussein Cancer Center in Jordan
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Breast cancer is the most common type of cancer among women worldwide, with increasing incidence rates, especially among younger populations. In Jordan, this cancer represents a significant portion of cancer cases, being diagnosed at more advanced stages and at younger ages compared to many Western countries. This article reflects the…
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Innovations of the Health Revolution: Towards a Sustainable Healthy Future
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## Introduction: The Importance of Innovation in Healthcare In an era characterized by rapid technological advancement and increasing health challenges, the urgent need for innovations in healthcare emerges as an appropriate solution to improve quality of life and reduce treatment costs. Statistics from the World Health Organization indicate that innovative…
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Alectinib as an Adjunct Treatment for ALK-Positive Non-Small Cell Lung Cancer: Efficacy and Safety in Post-Complete Resection Patients.
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In the face of ongoing challenges faced by lung cancer patients, the search for effective treatments that enhance survival and recovery rates continues. Lung cancer is one of the most common types of cancer, causing the deaths of millions of people annually. While surgical technology is considered a primary treatment…
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The role of exosomes in the diagnosis and treatment of liver cancer.
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In recent years, human health has faced increasing challenges due to the spread of malignant diseases, particularly liver cancer, which stands out as one of the most dangerous types. Liver cancer, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma, is one of the leading causes of cancer-related deaths worldwide. In this context,…
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The Role of Protein SUB1154 in the Immune Response of Dairy Cows Against Streptococcus uberis Infection.
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“Streptococcus uberis” is one of the pathogenic members of the pyogenic bacteria group and is considered a major cause of intramammary infections and mastitis in dairy cows. Despite its widespread distribution as an endemic pathogen, there is significant difficulty in controlling it worldwide, making it a major contributor to multiple…
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Innovations in Social Sciences: Tools and Methods for Understanding Societies in the Modern Era
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## Exploring Innovations in Social Sciences: Towards a Deeper Understanding of Societies ### Introduction: The Importance of Social Sciences in Modern Times Social sciences occupy a vital center in our contemporary societies, contributing to the understanding of the diverse dynamics that affect human behaviors and social relations. With the world…
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Innovation in Public Health: Comprehensive Strategies to Tackle Modern Challenges
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In an era characterized by rapid changes and unprecedented global challenges, innovations in public health have become an urgent necessity to meet the needs of healthy communities. The development of medical sciences and technology is accelerating, creating new opportunities to enhance access to healthcare and improve the quality of services…
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The Impact of Health Innovations on Communities: Towards a Better Future
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## Introduction: The Transformation of Healthcare Through Technology Current healthcare systems face significant challenges ranging from an increasing aging population to the rising burdens of chronic diseases. In this context, technological innovations become a pressing necessity, effectively contributing to changing the healthcare landscape and improving access to services. **South Korea**…
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Strange protein interaction in Escherichia coli with phage viruses to stimulate defense mechanisms against infection.
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The Introduction: The innate immune system in living organisms relies on a set of receptors known as “pattern recognition receptors” (PRRs), which play a vital role in detecting molecular patterns associated with pathogens. This article aims to explore how these receptors interact with what are known as pathogen-associated molecular patterns…
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Development of a Multicomponent Subunit Vaccine Against Mycoplasma Synoviae in Poultry
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“Mycoplasma synoviae” (MS) is considered one of the significant diseases affecting poultry worldwide, causing infectious arthritis and respiratory diseases, leading to substantial economic losses in the poultry industry. Despite progress in vaccine development, producing an effective commercial subunit vaccine against this pathogen remains challenging. In this article, we review a…
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Development of a Miniature Bioreactor System for Detecting Tumor Events in Human Blood Cell Culture
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Cell culture, both primary and secondary, is central to studying the biological behavior of cells in the field of scientific research. Research in immune cells, such as naïve lymphocytes and stem cells, is vital for understanding the complex processes occurring in the body. In this context, the researchers in this…
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Detection of Chromosomal Instability as a Diagnostic Tool for Predicting Lymph Node Involvement in Breast Cancer Pre-Surgery
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Breast cancer is one of the most common cancers among women worldwide, and its incidence rates have significantly increased in recent years. This type of cancer is characterized by a number of clinical challenges, particularly in assessing tumor spread and managing treatment stages. In this article, we highlight a new…
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Summary of the episode: Who has the right to edit genes, the state or the parents? | Fajnan Podcast
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This fascinating conversation addresses a complex topic that intertwines medicine and genetics with ethics and social implications. The speakers discuss a new technology known as “CRISPR,” which promises the ability to read and modify human genes. The concerns here revolve around the potential use of this technology to design “designer”…
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Superfast Polar Drills Ready to Search for the Oldest Ice
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Drilling ice cores is a tedious task. It takes years of fieldwork to recover long ice tubes that hold a continuous climate record spanning hundreds of thousands of years. Super-fast polar drills These speedy tools take about a week instead of years to penetrate several kilometers of ice. They break…
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Genetic Mutations in Multiple Endocrine Neoplasia Syndromes: Challenges and Strategies in Genetic Screening
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Multiple endocrine neoplasia (MEN) is a group of rare genetic disorders characterized by the development of multiple tumors in the endocrine system of the same patient. Since the introduction of the first type of MEN, MEN1, followed by MEN2A and MEN2B, the genes responsible for these syndromes have been identified,…
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New Advances in Managing Brain Metastases Due to Melanoma: A Rare Case of Early Pseudoprogression
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The points addressed in this article are considered sensitive and important topics in the management of tumor treatment, shedding light on recent developments in the treatment of brain metastases resulting from melanoma. As local treatments such as Stereotactic Radiosurgery (SRS) advance and the use of immunotherapies and targeted therapies increase,…
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Biotechnology: Innovations and Future Treatment Methods for Achieving Sustainable Health
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Biotechnology is considered one of the prominent modern fields that is bringing about radical changes in healthcare and medicine. In light of the major challenges facing the world today, such as epidemics and chronic diseases, the importance of these innovations in providing effective solutions that contribute to improving human health…
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CmdTAC System for Antiviral Defense in Escherichia coli: A Novel mRNA Editing Mechanism
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ADP-ribosyltransferases are considered essential elements in biology, characterized by their ability to transfer an ADP-ribose molecule from NAD+ to other biomolecules, contributing to the modification of amino acids in target proteins. The process of ADP-ribosylation is one of the most common post-translational modifications and plays a pivotal role in regulating…
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The spread of drug-resistant mutations to integrase inhibitors in Botswana before the switch to dolutegravir combination therapy
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The problem of drug resistance is one of the significant challenges facing the fight against the Human Immunodeficiency Virus (HIV), with the importance of studying drug resistance-related mutations continuously increasing. In this context, this article presents a comprehensive study on the prevalence of documented genetic mutations associated with resistance to…
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Increase in infection rates caused by non-tuberculous microbes in patients suspected of having tuberculosis.
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The incidence of non-tuberculous mycobacteria (NTM) is rising significantly worldwide, prompting attention from researchers and medical professionals, especially in routine diagnostic contexts and particularly for patients suspected of having tuberculosis. This study will present a comprehensive analysis of the genetic diversity of non-tuberculous mycobacteria in a sample of patients exhibiting…
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Improving the Condition of a Young Girl with Congenital Lupus Erythematosus through Blood Transfusion Therapy
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In newborns with neonatal lupus erythematosus, health challenges can be complex, especially when serious symptoms related to the blood system are involved. In this report, we present a special case of a girl aged one month and three days, who was transferred to the Children’s Hospital of Sichuan University, where…
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Comparison of Whole-Pelvic Radiation Therapy and Localized Radiotherapy in Response to Recurrent Prostate Cancer
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The recurrence of prostate cancer to the lymph nodes is one of the significant challenges in treating this health condition, requiring precise and research-based therapeutic strategies. This article presents important comparisons between two types of radiation therapies used in treating lymph node-restricted recurrences: Stereotactic Body Radiation Therapy (SBRT) and Whole-Pelvic…