Tag: GABA
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The Role of Tissue Inflammation in the Onset and Progression of Cognitive Impairments After Surgery and Its Impact on Elderly Patients
Cognitive disturbances post-surgery (POCD) are one of the serious health risks that patients may face after undergoing surgery under the influence of anesthesia, especially among the elderly. This condition is characterized by a decline in cognitive functions such as memory and concentration, adversely affecting patients’ quality of life and their return to daily activities. Although…
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Changing Generational Mood: How to Rethink the Relationship with Alcohol in a Culture that Spans Thousands of Years?
The phrase “Would you like to have a pint of beer?” is considered a fundamental element of British culture, akin to sipping tea, complaining about the weather, or even the historical document “Magna Carta.” This phrase gains special significance at five o’clock on Friday evening, when millions of Britons change their course towards the nearest…
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The Impact of Daily Disturbances on the Characteristics of Autism Spectrum Disorder and Its Potential Treatment
Autism Spectrum Disorder (ASD) is considered one of the complex early neurodevelopmental conditions, where multiple factors interfere with social interaction and motor behavior. With the increasing awareness and interest in research related to autism in recent years, scientific contexts have begun to reveal the relationship between biological rhythm disorders and the clinical condition of individuals…
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A New Strategy for Building a Causal Model of Brain Activity in the Fly Using Optogenetics and Statistical Analysis
The causal relationship in the nervous system is one of the most complex and challenging topics in neurobiology. Negative measurements of nerve activity are insufficient to infer these relationships, necessitating the need for experimental tools such as optogenetics. Despite advances in research in this field, there remains a lack of a clear approach on how…
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New Treatment for Autoimmune Encephalitis Using Evgartegimod: Three Case Reports of Rapid Symptomatic Improvement
Autoimmune encephalitis (AE) is a group of inflammatory disorders affecting the brain, reflecting an excessive immune response against the body’s own tissues. Among these conditions, encephalitis targeting N-methyl-D-aspartate receptors (NMDAR) ranks as the most common, followed by leucine-rich glioma-inactivated 1 (LGI1) receptor infections and γ-aminobutyric acid (GABABR) compound infections. Patients suffering from these inflammations experience…
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The Ratio of Arousal and Depression as a Biomarker for Assessing the Severity of Social Anxiety Disorder
Social Anxiety Disorder (SAD) is one of the most common psychological conditions, characterized by intense fear and excessive avoidance of social situations. Despite its significant impact on individuals’ quality of life, there remain challenges in accurately diagnosing it, as traditional methods heavily rely on self-reports and clinical interviews, which may lead to biases and inaccuracies…
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Paraneoplastic Neurological Syndromes Associated with Immunotherapy in Small Cell Lung Cancer: A Report of Two Cases
Amidst the rapid advancements in immunotherapies, particularly immune checkpoint inhibitors, the issue of side effects associated with these treatments emerges as a significant concern. Advanced small cell lung cancer (SCLC) is one of the aggressive malignancies that face immense treatment challenges, despite improved overall survival rates thanks to the combination of chemotherapy and immune checkpoint…