Tag: EGFR
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The Impact of Oxidative Balance on the Risk of Chronic Kidney Disease in American Adults
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Oxidative stress is considered one of the main factors in the causes of chronic kidney disease (CKD), significantly impacting kidney health and function. The “Oxidative Balance Score” (OBS) has been developed as a tool to measure overall oxidative status by integrating the oxidative and antioxidant effects resulting from nutrition and…
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Predicting Hepatocellular Carcinoma Outcomes Using a Novel Model Based on Anoxia Resistance and the Effect of the ERBB Pathway
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Hepatocellular carcinoma (HCC) is considered one of the most prevalent types of cancer, topping the list of diseases that pose a significant global health challenge due to its high mortality rate and low long-term survival rates. Despite remarkable advances in targeted therapy and immunotherapy, there remains an urgent need to…
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Alectinib as an Adjunct Treatment for ALK-Positive Non-Small Cell Lung Cancer: Efficacy and Safety in Post-Complete Resection Patients.
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In the face of ongoing challenges faced by lung cancer patients, the search for effective treatments that enhance survival and recovery rates continues. Lung cancer is one of the most common types of cancer, causing the deaths of millions of people annually. While surgical technology is considered a primary treatment…
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The role of exosomes in the diagnosis and treatment of liver cancer.
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In recent years, human health has faced increasing challenges due to the spread of malignant diseases, particularly liver cancer, which stands out as one of the most dangerous types. Liver cancer, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma, is one of the leading causes of cancer-related deaths worldwide. In this context,…
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Development of dual-specificity formulations to stimulate immune cells for cancer treatment using Vγ9Vδ2 T cells.
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The Vγ9Vδ2 T-cells are a unique type of immune cells that play a vital role in combating tumors and cancerous cells. Research presented by several prominent scientists in the fields of oncology and immunology shows how these tumor-killing cells can be harnessed through modern approaches such as the use of…
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The Impact of Racial Bias on Healthcare: Challenges and Outcomes of Its Use in American Medicine
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Racial Discrimination in Medicine: A Critical Analysis Race-based medical practices are a sensitive and complex topic within the American healthcare system, where scientific foundations intertwine with social and historical influences. In this article, we examine a serious issue known as “race calibration,” a practice that modifies medical test results based…
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Diagnosis of Pulmonary Gland Tumor: The Relationship Between Ground Glass Nodules, Tumor Extensions, and Molecular Testing Indicators
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Ground-glass nodules (GGNs) are considered early markers of lung cancer; however, the imaging characteristics and therapeutic effectiveness of many of these nodules as metastatic sites remain poorly defined. In this article, we highlight a unique case of lung gland cancer, where GGNs were identified as symptoms of pathological spread, with…
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Formonertinib as an Effective Treatment for a Patient with Non-Small Cell Lung Cancer with Rare HER2 Mutations
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In recent years, mutations in human epidermal growth factor receptor 2 (HER2) have become a growing topic of research and discussion in the field of non-small cell lung cancer (NSCLC). These mutations present significant therapeutic challenges, as their presence is typically associated with disease progression and poor response to conventional…
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Defining the Role of Chromatin Regulators in Lung Adenocarcinoma and Their Impact on Survival Outcomes and Immune Response
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Introduction: Lung cancer is a major source of cancer-related deaths, with incidence rates continuing to rise worldwide. Chromatin remodeling, as a vital biological process in regulating gene expression, is a key factor in the development and progression of malignant tumors. However, the role of chromatin regulators in lung adenocarcinoma (LUAD)…
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Different Models of Liver Regeneration in Zebrafish and Their Importance in Regenerative Medicine Research
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The process of liver regeneration is a central focus in gastrointestinal organ research, due to the unique ability of this organ to restore its tissues after exposure to injuries. Tropical fishes, such as the zebrafish (Danio rerio), serve as an ideal model in regenerative medicine, thanks to their remarkable capability…