Tag: CSF1R
Diagnosis and Treatment of Giant Cell Tumor in Tendon Using Genomic Sequencing and Single-Cell Analysis
Giant cell tumor of tendon sheath (TGCT) is considered a rare type of tumor that originates from the synovial sheath of joints and tendon sheaths. This tumor is characterized by the presence of recurrent genetic abnormalities, often related to the CSF1 gene, which poses many diagnostic and therapeutic challenges for physicians. Common symptoms include pain…
The role of TREM2 in the formation of fear-associated memory through the regulation of synaptic pruning by microglia.
The fear memory is considered one of the primary factors associated with psychological disorders related to fear and stress, such as post-traumatic stress disorder and phobias. Recent research has emerged to highlight the role played by microglial cells in shaping this memory, especially in the presence of synaptic deficiency and activation of microglia. While the…