Tag: CAR-T Therapy
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Strategies for Treating Relapsed Multiple Myeloma After BCMA-Targeted CAR-T Therapy Failure
The techniques of modified T cell therapy known as CAR-T are considered the cornerstone of a new era in the treatment of cancerous tumors, especially multiple myeloma (MM). Clinical studies, particularly those focused on targeting the B-cell maturation antigen (BCMA), have shown remarkable efficacy in patients with relapsed or treatment-resistant multiple myeloma. However, the challenge…
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Targeted Therapy for B Cells in Systemic Sclerosis: Prospects and Challenges
Systemic sclerosis (SSc) is considered one of the complex autoimmune diseases that significantly affect patients’ quality of life, as it leads to a decline in immune system activities, vascular damage, and fibrosis in tissues. B cells play a pivotal role in the development of this disease by producing autoantibodies and secreting cytokines, contributing to the…
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The Role of Immune Cells in Antigen Presentation in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most prominent types of cancers affecting the liver, posing a significant challenge to public health due to high rates of incidence and mortality. Immune cells play a vital role in the context of this disease, particularly regarding antigen presentation, which forms the crux of this review. In this…
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“Exploring Space: Horizons of Innovation and Global Cooperation Towards a Sustainable Future”
Space exploration is one of the most prominent subjects that piques human curiosity and drives innovation and discovery. In our current era, this field has gained special importance, impacting various aspects of life, whether scientifically, economically, or even environmentally. According to specialized reports, such as those issued by **McKinsey** on the future of space, economic…
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Advanced Options for Treating Rheumatoid Arthritis
Rheumatoid arthritis is considered one of the complex autoimmune diseases that previously lacked effective treatment options, leading to severe issues in joint formation and the quality of life for patients. However, recent years have witnessed significant advancements in treatment development, providing millions of patients with hope for better management of this disease. This article addresses…
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Viral Therapy as a New Approach to Cancer Treatment: Focusing on Multiple Myeloma
Viral therapies used in tumor treatment, known as oncolytic viral therapy, are among the modern therapeutic approaches that have garnered interest in the medical community for treating certain types of cancer, including multiple myeloma. This article addresses a comprehensive discussion of the mechanisms by which oncolytic viruses target cancer cells, highlighting their potential role in…