Tag: biomarkers
-
MicroRNA and its Role in Regulating Autophagy and Neurodegenerative Diseases
•
Neurodegenerative diseases are one of the prominent health challenges facing society in our current era, especially with the increasing aging of the population. This category of diseases, such as Alzheimer’s and Parkinson’s, is characterized by the accumulation of abnormal proteins in nerve cells, leading to the deterioration of neurological functions.…
-
Identification of Distinct Genes and Immune Patterns Associated with Abdominal Aortic Aneurysm Diseases
•
Aortic aneurysm (AAA) is a life-threatening vascular condition characterized by an abnormal widening of the aorta in the abdominal area, which can lead to rupture and significant life risks. This article discusses the latest studies aimed at discovering new indicators for the early detection of AAA and focuses on the…
-
Bibliometric Analysis of Research on Tripartite Lymphatic Structures and Their Role in Immunity and Immunotherapy
•
Secondary lymphoid structures (TLS) are one of the most fascinating subjects in modern immunology research, revealing new aspects of the body’s response mechanisms to tumors. Despite the increasing interest in this field, comprehensive studies using bibliometric analysis to examine the related examinations of these structures have not yet been conducted.…
-
Changes in Structural Network Properties and Gray Matter Volume in Patients with End-Stage Kidney Disease Without Cognitive Impairment
•
Chronic kidney diseases pose an increasing health challenge worldwide, with estimates suggesting that the number of patients with chronic kidney diseases may reach 700 million, accompanied by a significant rise in mortality rates associated with them. As public health concerns escalate due to this increase, interest continues to grow in…
-
The Effect of Biochar and Compost Mixtures on the Growth and Tolerance of Brassica napus to Lead in Contaminated Soil
•
Soil contamination by heavy metals is a serious issue that occupies a significant place in global concern due to its negative impacts on humans, plants, and the environment. Lead (Pb) is considered one of the most toxic metals, as it records harmful effects on agricultural growth and human health, especially…
-
Technological Innovations in Healthcare: Transforming the Future and Improving Patient Outcomes
•
### Introduction: The Importance of Health Technology in Improving Care In our modern age, health technology has become one of the foundational pillars in the development of healthcare systems. In the face of increasing health challenges, such as the outbreak of epidemics and rising rates of chronic diseases, technological solutions…
-
Pushing the Physical Boundaries of Wave Propagation in Soft Tissues: An Addition to Short-Wave Stiffness Imaging
•
Shear Wave Elastography Imaging (SWEI) is one of the most important developments in the field of tissue imaging, as it relies on measuring shear waves to assess the stiffness of biological tissues. The level of tissue stiffness is associated with several serious diseases, such as breast cancer, prostate cancer, and…
-
Innovations in Healthcare: Steps Towards Improving Quality and Efficiency
•
### Exploring Innovations in Health: Towards Advanced and Comprehensive Healthcare ## Introduction: The Importance of Innovation in Health for Improving Care In an era fraught with increasing health challenges and rapid technological advancement, innovation in the health sector has become a pressing necessity to meet the growing needs of society.…
-
The Role of lncRNA GRASLND in Melanoma Differentiation and Progression and Its Impact on Immune Response
•
Melanoma is one of the most dangerous types of skin cancer, characterized by its high ability to spread and its precision in adapting to its environment. Understanding the molecular mechanisms that lead to these properties is vital for developing effective therapeutic strategies. In this article, we explore the role of…
-
Microsgel-Based Etalon Film: Properties and Characterization
•
Microgel-based membranes represent an innovative type of adaptive material, allowing dynamic responses of the membranes to various environmental stimuli. In this research, we explore microgel-based etalon membranes (MEMs), where stimulus-responsive microgel particles are integrated with an optical device used to filter specific wavelengths of light. Through this integration, microgel-based membranes…
-
The Interaction Between Thyroid Disorders and Diabetic Retinopathy: An Analysis Using Randomized Mendelian Approaches
•
In the world of medicine, the relationship between thyroid dysfunction and complications of diabetes emerges as an important research area, especially in the context of its impact on diabetic retinopathy. Recent studies indicate that individuals with diabetes are more susceptible to thyroid problems, making the understanding of this relationship vital.…
-
AI Analysis of CT Scan Images to Assess Plaque Characteristics and Risks in Patients with Type 2 Diabetes and Hypertension
•
In recent decades, modern technology has emerged as a significant factor in various fields of medicine, with one of the most notable advancements being the use of artificial intelligence in diagnosing heart diseases. This article aims to explore how this technology can contribute to improving the assessment of heart diseases,…
-
The Role of Tissue Inflammation in the Onset and Progression of Cognitive Impairments After Surgery and Its Impact on Elderly Patients
•
Cognitive disturbances post-surgery (POCD) are one of the serious health risks that patients may face after undergoing surgery under the influence of anesthesia, especially among the elderly. This condition is characterized by a decline in cognitive functions such as memory and concentration, adversely affecting patients’ quality of life and their…
-
The Impact of Oxidative Balance on the Risk of Chronic Kidney Disease in American Adults
•
Oxidative stress is considered one of the main factors in the causes of chronic kidney disease (CKD), significantly impacting kidney health and function. The “Oxidative Balance Score” (OBS) has been developed as a tool to measure overall oxidative status by integrating the oxidative and antioxidant effects resulting from nutrition and…
-
Study of the Characteristics of Calcium Channels TRPC1 and TRPC5 and Their Effects on Neural Response
•
Transient Receptor Potential Cation Channels (TRPC) are vital elements in many physiological processes, playing a crucial role in regulating calcium flow and membrane potential. The study presented in this article focuses on TRPC5 channels, which are considered a non-selective cation channel that contributes to membrane depolarization, and explores the structural…
-
Exploration of Metabolome Components in a 3D Culture Model of Colon Cancer and Adipocytes
•
Introduction: Colon and rectal cancer (CRC) is considered one of the most common and lethal types of cancer worldwide, ranking third in incidence and second in mortality. Research reveals an increasing association between obesity and the onset of this disease; however, several aspects remain to be clarified, especially concerning the…
-
PD-1 expression on tumor-infiltrating lymphocytes as a predictive factor in early-stage non-small cell lung cancer
•
Lung cancer of the non-small cell type (NSCLC) is considered one of the deadliest cancers worldwide, making it a major focus of medical research. In recent years, immunotherapies have transformed the management of this disease, with proteins such as PD-1 and PD-L1 representing critical pathways in the therapeutic field. This…
-
Innovations in Biotechnology: Toward a Healthy and Sustainable Future
•
Biotechnology is considered one of the leading fields that reshapes the future of public health and the environment. The world today is experiencing a dynamic phase that demands rapid innovation and development to meet increasing challenges, such as pandemics, chronic diseases, and environmental pressures. Research and innovations in this field…
-
Gene Therapy for Hemoglobin-Related Diseases: Progress and Challenges
•
Hemoglobin-related diseases, such as sickle cell anemia and beta-thalassemia, are common single-gene disorders that affect millions of people worldwide. The challenges faced by traditional treatments for these diseases, which often focus on symptom management and stem cell transplantation, drive researchers towards developing new and more effective solutions. In this article,…
-
Innovations in Mental Health Care: Toward a Comprehensive Support System for Mental Well-Being
•
**Exploring Innovations in Mental Health Care: Towards a Comprehensive Health Support System** Mental health is an integral part of public health, playing a pivotal role in shaping individuals’ quality of life and daily experiences. In a rapidly changing world with increasing psychological and social pressures, there is an urgent need…
-
Identification of the pathological mechanisms and key genes associated with the activation of Epstein-Barr virus and long COVID.
•
The condition known as “long COVID” is one of the prominent topics in contemporary health research, with numerous studies focusing on the effects of infection with the novel coronavirus (SARS-CoV-2) that persist long after recovery. In this context, attention is directed towards the role of Epstein-Barr virus (EBV) reactivation as…
-
Technological Innovations in Healthcare: Transforming the Future and Improving Patient Outcomes
•
### Introduction: The Importance of Health Technology in Improving Care In our modern age, health technology has become one of the foundational pillars in the development of healthcare systems. In the face of increasing health challenges, such as the outbreak of epidemics and rising rates of chronic diseases, technological solutions…
-
Strategies for Treating Relapsed Multiple Myeloma After BCMA-Targeted CAR-T Therapy Failure
•
The techniques of modified T cell therapy known as CAR-T are considered the cornerstone of a new era in the treatment of cancerous tumors, especially multiple myeloma (MM). Clinical studies, particularly those focused on targeting the B-cell maturation antigen (BCMA), have shown remarkable efficacy in patients with relapsed or treatment-resistant…
-
The Role of Factor D in Cardiovascular and Metabolic Diseases
•
Cardiovascular and metabolic diseases (CVMDs) are among the leading causes of death worldwide, especially with their increasing prevalence in light of current health conditions. Adipose tissues play a pivotal role in the development of these diseases, with one of the main aspects being the relationship of complement factor D (CFD)…