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Should scientists infect healthy individuals with the coronavirus to test vaccines?

In March 2020, a radical proposal is being discussed for conducting “human challenge” studies, where a small number of healthy volunteers are infected with the virus to rapidly test the vaccine. This bold proposal could help accelerate vaccine research.

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The study can be accessed by joining the academic institution or subscribing to the journal. You can subscribe to the journal for full access to the print issue and online access.

The Radical Proposal for Vaccine Testing

Amid the spread of the virus and millions, perhaps billions, of people avoiding social interaction to protect themselves and their communities from coronavirus, a radical research proposal is being discussed that could help stop the pandemic. This proposal involves infecting a small number of healthy volunteers with the virus to rapidly test the vaccine.

Access Options

The study can be accessed by joining the academic institution or subscribing to the journal. You can subscribe to the journal for full access to the print issue and online access.

Changing Institutions

If you wish to change the institution you are using to access the study, you can change your registered institution for access.

References

This interview has been edited for clarity and simplicity. You can view the references used in the study through the following links:

  • Eyal, N., Lipsitch, M. & Smith, P. G. J. Infect. Dis. https://doi.org/10.1093/infdis/jiaa152 (2020).
  • Article on Google Scholar

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Source: https://www.nature.com/articles/d41586-020-00927-3


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