The highly precise genome editing technology, known as base editing, has entered a new phase: the first clinical trials using this technology have been conducted in the United States. These trials employ more complex genome modifications than those performed on humans so far. This technology is used in the treatment of genetically modified T lymphocytes for the treatment of lymphocytic leukemia.
Base Editing Technology
Base editing is an advanced technique for high-precision genome modification. This technology utilizes an enzyme called “base editor” to make specific modifications to the cell’s genome. Base editing is considered more precise than traditional CRISPR technology, as it can perform fine adjustments to the genome with nucleotide-level accuracy.
Clinical Trials in the United States
The first clinical trials using base editing technology have been conducted in the United States. These trials involve more complex genomic modifications than those performed on humans so far. Base editing is being tested in the treatment of genetically modified T lymphocytes for lymphocytic leukemia. Researchers hope that this technology will help enhance the effectiveness of leukemia treatments and provide new therapeutic options for patients.
Future Developments
With the introduction of base editing technology into clinical trials in the United States, researchers expect it to be developed and improved in the future. This technology may contribute to enhancing the effectiveness of leukemia treatments and providing tailored and effective therapies for patients. The use of base editing technology in the treatment of lymphocytic leukemia represents a significant step toward advancing the field of gene therapy and improving treatment outcomes for patients.
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