How the brain feels after a flu infection – and orders the body to rest.

Scientists tracked the nerve cells in the throat that detect signs of infection and relay this information to the brain.

Introduction

The flu can make even the toughest individuals lie on their beds and lose their appetite. Now, nerve cells in mice have been identified that inform the brain of the presence of a flu infection, leading to reduced movement, hunger, and thirst.

How the Brain Senses Flu Infection

Scientists have tracked the nerve cells in the throat that detect signs of infection and relay this information to the brain. When a flu infection is detected, these nerve cells are activated and send signals to the brain. The brain receives these signals and works to regulate the physiological response to the infection, resulting in decreased movement, hunger, and thirst.

The Effects of Flu Infection on the Body

When infection signals are sent from the nerve cells in the throat to the brain, an impact occurs on the body. The brain reduces movement, as the person with the flu feels tired and weak, preferring to lie in bed. The brain also reduces appetite and thirst, leading to a loss of appetite and desire for food and fluids.

The Importance of the Study

This study helps in understanding how the brain senses infection and regulates its response. This knowledge may assist in developing more effective treatments for the flu and improving patient comfort during the infection. This study may also contribute to understanding other diseases related to the nervous system and how they affect the body.

Conclusion

Scientists have concluded that there are nerve cells in the throat that detect signs of infection and send signals to the brain. The brain responds by regulating the body’s response to the infection, leading to reduced movement, hunger, and thirst. This study contributes to understanding how the brain works and how it affects the body during a flu infection and may help in developing more effective treatments for patients.

Source: https://www.nature.com/articles/d41586-023-00675-0

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