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A New Interpretation of Infertility: Oocytes Missing the Mysterious “Network”

The discovery of a “storage reservoir” for essential proteins may explain some cases of infertility.

Revealing the Cellular Network of Proteins

For nearly 60 years, scientists have wondered about the purpose of the fiber bundles floating in oocyte cells. A study published today in Cell reveals that these fibers, known as the cellular network, are storage sites for many proteins essential for early embryo development. This discovery could explain why individuals whose oocytes completely lack these fibers suffer from infertility.

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Updates and Corrections

Incorrect information for reference 1 has been corrected as of November 3, 2023.

References

Jentoft, I. M. A. et al. Cell https://doi.org/10.1016/j.cell.2023.10.003 (2023).

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Related Fields

– Developmental Biology.

– Cellular Imaging.

– Cell Biology.

Source: https://www.nature.com/articles/d41586-023-03415-6


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