Modeling approaches for development are our way for 2023, due to the significant contributions made by modern methodological advancements in our understanding of the molecular mechanisms of human embryogenesis.
Focus
Lab-grown embryo models, supported by advancements in adjacent fields, have changed our understanding of embryonic formation.
How to Build a Virtual Embryo
Human embryos and embryo models, which are this year’s method, can easily be studied. In contrast, digital embryos can be studied, and even computational experiments can be conducted to see what happens.
Development of Embryo Models
The creation of multi-source models derived from stem cells for mammalian embryo formation opens many new avenues for studying human development and requires scientists to clarify the ethical issues associated with it.
How Evolutionary Cell Maps Affect Stem Cell Embryo Models
Maps of body development provide a critical reference argument for the new category of human embryo models derived from stem cells, helping to accelerate ideas about human developmental mechanisms.
Tracing Developmental Lineages
I discuss how recent advancements in lineage tracing methods enable insights into the fate and path of the cell during development.
Culture of Mammalian Embryos in the Laboratory
Advancements in methods that enable the culture of mammalian embryos in the laboratory have become a fundamental approach to exploring early mammalian embryonic development and modeling developmental and pregnancy-related disorders. Here, we discuss the evolution of modern techniques in this field and analyze current challenges and future trends.
Embryonic Shape Drawing and Mechanics in Embryo Models
Recent methodological advancements in measurements of engineering and forces in early embryos and their models enable a deeper understanding of the complex interplay between genetics, mechanics, and engineering during development.
Ethics of Human Embryo Model Research
Human embryo models derived from stem cells in the laboratory raise new ethical questions and highlight ongoing questions surrounding research on human embryos.
Monitoring Methods
Advancements will enable the determination of proteomic architecture at the cellular level.
Large Genomic Models
Large language models learn the language of the genome.
Mapping the Human Brain
High-resolution imaging of human brain connections represents the next frontier in neuroscience.
From Genome Structure to Function
Advancements in chromosome structure determination help uncover the regulatory roles of gene organization.
Nanopore Protein Sequencing
Advancements in peptide detection and sequencing based on nanopores show promise for breakthroughs.
Imaging Across Scales
New developments in established methods and multimodal imaging are about to bridge the gaps between cellular and tissue imaging.
Local Multiscale Omics
Local multiscale omics provide a collective approach to capturing molecular information in complex tissues.
Synthetic Tissue Environments
Synthetic environments for cellular matrices enable the reconstruction of tissue environments.
Monitoring Methods
Advancements will enable the determination of proteomic architecture at the cellular level.
Large Genomic Models
Large language models learn the language of the genome.
Mapping the Human Brain
High-resolution imaging of human brain connections represents the next frontier in neuroscience.
From Genome Structure to Function
Advancements in chromosome structure determination help uncover the regulatory roles of gene organization.
Nanopore Protein Sequencing
Advancements in peptide detection and sequencing based on nanopores show promise for breakthroughs.
Imaging Across Scales
New developments in established methods and multimodal imaging are about to bridge the gaps between cellular and tissue imaging.
Local Multiscale Omics
Local multiscale omics provide a collective approach to capturing molecular information in complex tissues.
Synthetic Tissue Environments
Synthetic environments for cellular matrices enable the reconstruction of tissue environments.
Source: https://www.nature.com/collections/ejcfiieddc
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